Process of IVF / ICSI cycle with Donor eggs and Embryo transfer in recipient
Your detailed history, including past medical and surgical details and review of relevant past investigations helps us to decide the plan of action.
When you confirm your plans for treatment with egg donation in India and your partners sperms with embryo transfer in you, the following processes are involved :
Egg Donor’s Involvement
This includes tests on your partner and the egg donors to prepare for further treatment.
Selection of Egg donor
Donor profiles are submitted to you. Detailed history and the features of the donors are provided. Infection screens and baseline tests are mostly done when profiles are sent for selection. Name identities are not provided to ensure confidentiality. Only when you approve the donor we start the further process. This can take 4 to 6 weeks.
A thorough counseling session with the egg donor is undertaken to ensure that she understand the process fully and are doing an informed choice. They can still walk away at this stage without any obligation.
Egg Donor Evaluation
At this stage we ensure that all detailed tests such as infection screen (HIV, Hepatitis B and C, VDRL and CMV), cytogenetic tests (karyotyping), Haemoglobin electrophoresis and so on are available. Any other tests that you may request will also be performed.
Cycle Cordination followed by Down Regulation
The donor and your menstrual periods are coordinated. Down regulation injections (GnRH injections) are started on the donor and you towards the 21st day of the period. These are given till one day before the egg collection procedure.
Hormonal injections are given to the donor to stimulate egg production in her ovaries. These are needed for 10 to 11 days.
Travel to India
You should plan to travel to India two to three days before the donors egg collection.
Around the 14th day, the donors egg collection is performed in our dedicated IVF theatre. After this stage, the donors involvement is finished. A fresh sample is taken from your partner on the day for the further process. We provide a special en-suite room for this purpose.
IVF/ICSI Laboratory Work
Further work with the eggs and the sperms takes place in our state of the art embryology laboratory. Embryos are incubated in the special incubators till the day of embryo transfer (day 3 or 5). During the time that the egg donors treatment is going on, your preparation is done for the embryo transfer
Your Preparation for Embryo Transfer
Cycle coordination followed by Down regulation
The donor and your menstrual periods are coordinated. You are given OC pills from the second day of your period to control the period date. This can be given by your local GP. Down regulation injections (GnRH injections) need to be taken locally on the day when we stop your pill (towards the 22nd day of your period). You are then likely to get a period. Please inform the first day of the period to the hospital. The injections are continued till one day before the egg collection procedure. As the doctors at Springs hospital are licensed to practice in the UK, the above prescriptions can be written by the Springs hospital to make the local process easy for you.
Preparing the lining of the womb
Another hormonal tablet is given to you from the second day of your period on a daily basis to ensure that the lining of your womb grows well. This helps the implantation after the embryo transfer. On the seventh day, we may request an internal scan to check that the lining of the womb is growing well. This will have to be done locally. If this is done privately, there would local costs, which are not included in the price packages. These tablets are continued even after the pregnancy happens and reviewed later.
The selected surrogate undergoes detailed tests such as infection screen (HIV, Hepatitis B and C, VDRL and CMV), cytogenetic tests (karyotyping), Haemoglobin electrophoresis and so on. Any other tests that you may request will also be performed.
Other supporting treatment to the surrogate mother
Progesterone is given to you from the day of the egg collection. This is continued till the pregnancy test and thereafter reviewed.
Transferring the embryos to the womb
Generally 3 to 5 days after the egg collection, the embryos are ready to be transferred to you. We check all the available embryos and grade them. The selected good ones are then transferred to you.
Other Supporting treatment to the Surrogate Mother
Progesterone is given to the surrogate mother from the day of the egg collection. This is continued till the pregnancy test and thereafter reviewed.
Transferring the Embryos to the Womb
Generally 3 to 5 days after the egg collection, the embryos are ready to be transferred into the surrogate mothers womb. We check all the available embryos and grade them. The selected good ones are then released into the surrogate mothers womb gently.
Return to Home
After the embryos are transferred, you could return home anytime. Some prefer to stay rested for the first 5 days while the implantation process is happening inside the body. In total, your stay in India could be between 7 to 10 days.
This important day is generally the 14th day after the embryos are transferred to you. The levels of B HCG in the surrogate mothers blood are tested to detect pregnancy. This may have to be repeated 48 hours later to check if the levels are rising adequately.
Once the pregnancy is confirmed, the further antenatal care is continued at your local hospital.
The Origin’s Involvement
Our internationally trained experts will review your history and all previous treatment (including investigations) to give you a truly expert opinion.
Based on our evaluation of your case and the opinion provided, you are expected to make an informed choice of further treatment. Together we then take the matter further. This may include choosing a suitable egg donor or a surrogate mother. Sometimes surgery may appear necessary to improve our success rates. If this is chosen, we can organize this for you. Blood, semen or any other test required in your case can be organized by us. The best part is all these services are provided within the three floors of the Springs centre.
Once the background evaluation, planning and preparation is complete, we put a schedule in place so that you can start making your arrangements to visit us. Our dedicated fertility coordinator works on each case with an individual attention to ensure smoothness throughout.
We mediate on your behalf to make sure that all parties are well informed of the terms and conditions of the agreement. Tuning expectations is an important aspect of this treatment. We also ensure that the surrogates and the donors interests are looked after. They are provided the emotional, physical, social and financial support. Our egg donors and the surrogate mothers are very happy and satisfied with our services. When fairness, transparency, sincerity and honesty is guaranteed the whole process becomes enjoyable for all.
The Springs’s support services such as pathology, pharmacy, scanning, counseling and so on are available at all times for our patients.
Superspecialist Medical management
Our doctors are trained in UK for over 12 years. They have worked as specialists in these fields in UK for many years. They have also worked in USA. This has provided them a first hand experience of advanced medical care in the following fields.
We employ the services of a lawyer to look after the legal matters for egg donation in india. This is moreso important when surrogate mothers are involved. A detailed agreement covering all the agreed terms and conditions is signed by all parties. All are then expected to abide by this agreement. Legal hastles are rare, but the presence of a legal agreement provides a sense of security to all involved. If sincerity, honesty and transparency is maintained by all throughout the process, then the need to refer to this legal agreement would be even rarer.